Endocrine Abstracts

IntroductionThe Carney Complex (CNC) is a rare, autosomal dominant, multiple endocrine neoplasia. It involves multiple endocrine glands, cardiac and skin myxomas, mammary fibroadenomas and mucocutaneous pigmentation. Cushing’s syndrome, due to primary pigmented nodular adrenocortical disease (PPNAD), is described in 25% of the cases.Case reportWoman, 21-year-old, was refered for secondary amenorrhea. Med...

Introduction: The tendency to eat salty foods is an individualized matter. Aldosterone plays an important role in this increase in salt appetite. In this study the effects of different salt concentrations during pregnancy on Na and aldosterone level, adrenal gland and salt appetite of rat’s infants and the relation of salt consumption with Bp were studied.Method: Eight groups of rats, six rats in each group, (ones of male and five female) having 200...

Introduction: There are emerging reports showing the relationship between human immunodeficiency virus (HIV), Covid-19 and adrenal insufficiency. This was attributed to thrombotic events and necrosis, leading to hypoadrenalism. The HIV virus can also lead to Addison”s disease due to destruction of adrenal gland. Prevalence of adrenal infarction with COVID-19 was found to be 23% and 88% this was shown to be affecting both adrenal glands. Case report:...

Introduction: Basal ganglia calcification or Fahr’s Syndrome is a rare form of neurological disorder. Its prevalence goes from 2 to 12.5 %. It can be primary (idiopathic) or secondary (from metabolic disorders especially from hypoparathyroidism).We present the case of a female patient with hypoparathyroidism and secondary Fahr’s Disease.Case description: The patient L.J. 61 years old, from Pogradec, Albania, who came to the emergency room wit...

Introduction: There have been described that about 50% of women diagnosed with PCO-S, present lipid metabolism disorders, insulin resistance and incorrect blood pressure. They suffer not only from fertility disorders, but also present a risk of metabolic complications such as: obesity, type 2 diabetes and hypertension, which increase diet-related cancers and cardiovascular risk.Aim: To explore if serum omentin concentration could be an indicator of cardi...

Spontaneous remission of Cushing disease might be a phase of cyclic disease, but could also be explained by an ACTH-microadenoma infarction or hemorrhage. True remission must be differentiated from cyclic Cushing’s disease with prolonged follow up. 63-years-old female patient was referred to endocrinologist’s and presented with uncontrolled hypertension, type 2 diabetes, central obesity, hirsutism, swelling of the face and legs and a ’buffalo hump’. After a...

BackgroundCardiovascular complications of Cushing’s syndrome (CS) include; hypertension, left ventricular hypertrophy, and myocardial ischaemia. Also, CS can cause structural and functional changes in the heart, leading to dilated cardiomyopathy in rare cases. Here, we present a case with dilated cardiomyopathy related to Cushing’s syndrome.CaseA 31-year-old male patient applied to the cardiology de...

It is known that disoaders of the hypothalamic-pituitary-adrenal system and excess glucocorticoids in Cushing’s disease (CD) can significantly affect various organs and systems, in particular, the secretion of pituitary hormones. However, in the literature there is practically no work on the assessment of the state of tropic hormones and hormones of the peripheral glands in the early postoperative period after transsphenoidal adenomectomy. The aim of this study was to ass...

Introduction: Subclinical Cushing’s syndrome refers to autonomous cortisol secretion in patients who do not have the typical signs and symptoms of hypercortisolism. This study was undertaken to describe clinical, biological and radiological features of this disease and to evaluate the clinical outcome after surgical and medical treatment.Methods: Retrospective study conducted over a period of 12 years and including 17 patients hospitalised in our de...

Introduction: Cushing’s disease is diabetogenic due to the insulin resistance generated by the stimulating effect of glucocorticoids on neoglucogenesis and hepatic glycogenolysis.GoalAim of our work is to study the frequency and characteristics of diabetes mellitus during Cushing’s disease.Material and Methods: Retrospective study of a sample of 100 patients collected between (January 1983 –...